Downside To Doxycycline Treatment For Acne. The antibiotic doxycycline is considered to be a kinder, gentler alternative to minocycline, an antibiotic more often used to treat acne in the United States. Doxycycline, like other tetracycline antibiotics, is bacteriostatic. It works by preventing bacteria from reproducing through the inhibition of protein synthesis. Esophagitis has several common causes: Acid reflux — By far the most common cause of esophagitis is acid reflux (also called gastroesophageal reflux disease or GERD). Prevention. Since there can be many causes underlying esophagitis, it is important to try to find the cause to help to prevent esophagitis. To prevent reflux esophagitis, avoid acidic foods, caffeine, eating before going to bed, alcohol, fatty meals, and smoking. Doxycycline is a prescription antibiotic medication indicated for the treatment of certain infections and diseases. Learn about side effects, drug interactions, dosages, warnings, and more. Esophagitis is a condition in which the lining of the esophagus becomes swollen, inflamed, or irritated. The esophagus is the tube that leads from your mouth to the stomach. Learn about the potential side effects of doxycycline. Includes common and rare side effects information for consumers and healthcare professionals. Treatment for esophagitis depends on the underlying cause and the severity of tissue damage. If left untreated, esophagitis can damage the lining of the esophagus and interfere with its normal function, which is to move food and liquid from your mouth to your stomach. These 10 medications cause direct injury to the lining of the esophagus. 1) Doxycycline. Doxycycline is an old antibiotic used for numerous conditions including rosacea, acne and Lyme disease. Learn about Oracea (Doxycycline) may treat, uses, dosage, side effects, drug interactions, warnings, patient labeling, reviews, and related medications.